Item – Thèses Canada

Numéro d'OCLC
1006918636
Lien(s) vers le texte intégral
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Auteur
Léonard, Stéphanie,1974-
Titre
Specificity of relationships among vulnerability factors and symptom dimensions in Bulimia Nervosa.
Diplôme
M. Sc. -- McGill University, 1998
Éditeur
Ottawa : National Library of Canada = Bibliothèque nationale du Canada, [2001]
Description
1 microfiche
Notes
Includes bibliographical references.
Résumé
Bulimia Nervosa (BN) is believed to have a multidimensional causality including developmental factors and neurobiological vulnerabilities. This study examined diverse clinical features (e.g., binge and vomit frequency, eating attitudes, impulsivity, dissociative symptoms, and affective instability) and two putative causal agents (e.g., childhood sexual/physical abuse and serotonin abnormalities) in bulimics with and without a comorbid Borderline Personality Disorder (BPD). Twenty-seven BN sufferers and 25 normal-eater controls underwent a multidimensional assessment of eating symptoms, psychiatric symptoms, personality disturbances, experiences of childhood abuse and serotonin (5-HT) dysfunction. The latter was measured using paroxetine binding in blood platelets. In contrast to control subjects, borderline and nonborderline bulimics both displayed comparable abnormalities on paroxetine binding Bmax measure and eating symptomatology, whereas the borderline bulimics alone displayed particular elevations on measures of childhood trauma, impulsivity, dissociation, and to some extent affective instability. We interpret our results as suggesting that problems of 5-HT neurotransmission may be associated generally with BN, whereas developmental abuse may be relevant to characterological disturbances seen in only a subset of BN sufferers.
ISBN
0612508161
9780612508163